NephMadness 2019

NephMadness is a nephrology-focused online interactive medical education activity. While it has been around for 7 years, this is the secondyear that CME/CE credit will be offered for players, and first for MOC! Social media, interactivity, and gamification will teach the latest advances and the most important breakthroughs in nephrology.

There are 8 general themes (called “regions”) broken down into 4 specific concepts (called “teams”). Teams compete against each other in a single elimination contest. We have selected content experts from each region to make sure the information we present is accurate, unbiased, and interesting. For details, read the explanatory post here.

Target Audience

  • Physicians
  • Read the 8 “region” summaries that cover the 32 nephrology concept teams at the AJKD blog here. Earn up to 1.0 credit per region.
  • Complete a bracket with your predictions of what concepts are the most important or most impactful here
  • Participate in social media (Twitter, Instagram, Facebook, blogs) discussions about these concepts, sharing your opinions of what is the most important or impactful to you in nephrology.
  • Login or create an account to this site and complete the evaluations and download certificates.

Learning Objectives

After this activity learners will be better able to:

  • Discuss the current guidelines and updates for the treatment of hypertension
  • Review the updated diagnosis and treatment algorithms for primary hyperaldosteronism
  • Review technological advances in volume assessment and compare them to traditional methods 
  • Identify the benefits of achieving dry weight in patients on hemodialysis and the adverse patient reported outcomes that may be associated
  • Define the role of complement in the pathophysiology of C3 glomerulopathy and how it guides treatment
  • Identify the role of terminal complement inhibitors that are currently available, in addition to novel inhibitors that are currently being tested for more specific targets in the complement pathway
  • Identify the spectrum of kidney injury that can occur as a result of the physiology associated with extreme exercise and toxicities that can occur with supplements
  • Identify the role, risks, and benefits of exercise in patients with end-stage kidney disease on dialysis, and also in patients who have receive kidney transplants 
  • Recognize the role of NSAIDs, opiates, and other medications for pain management in patients with kidney disease
  • Review the use of angiotensin-converting-enzyme inhibitors (ACE-I) and PRN’s in hospitalized patients Identify the pros and cons of various isotonic crystalloid solutions for the use of volume resuscitation in hospitalized patients
  • Recognize the role of bile-acids and bilirubin in the role of nephrotoxicity in the setting of patients with advanced liver disease
  • Identify the medical treatment options for hepatorenal syndrome.Identify the role of plasma exchange in the treatment of antineutrophil cytoplasmic antibodies (ANCA) vasculitis as well as multiple myeloma and cast nephropathy
  • Identify the role of plasma exchange in both the pre and post-transplant period for both optimization of graft function and prevention of recurrent disease
Additional information
2018 NephMadness Bracket 562.33 KB
Course summary
Course opens: 
Course expires: 

Please see individual activities (by bracket) for their faculty information. 

The National Kidney Foundation is accredited by the American Nurses Credentialing Center (ANCC), the Accreditation Council for Pharmacy Education (ACPE), and the Accreditation Council for Continuing Medical Education (ACCME), to provide continuing education for the healthcare team.



The National Kidney Foundation designates this enduring activity for a maximum of 8.0 AMA PRA Category 1 Credit(s) TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Available Credit

Accreditation Period

Course opens: 
Course expires: 
Please login or register for a PERC account to take this course.


Please login or register for a PERC account to take this course.

The faculty and National Kidney Foundation (NKF) do not recommend the use of any pharmaceutical, diagnostic test, or device outside of the labeled indications as approved by the FDA. Please refer to the official prescribing information for each product for approved indications, contraindications, and warnings.

Information contained in this NKF educational resource is based upon current data available at the time of publication. Information is intended to help clinicians become aware of new scientific findings and developments.  This NKF educational resource is not intended to set out a preferred standard of care and should not be construed as one. Neither should the information be interpreted as prescribing an exclusive course of management.

Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every healthcare professional making use of information in this NKF educational resource is responsible for interpreting the data as it pertains to clinical decision making in each individual patient.